December Newsletter
Dear MDS Center Community,
Please see below for our December news and announcements.
Please direct any questions to fs291@cumc.columbia.edu
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MDS Center Programs
E.P. Evans MDS Center Hematological Malignancies Seminar Series:
Wednesday, January 10 ,2024
12:00 PM to 1:00 PM
ICRC first floor auditorium
Rudd Delwel, PhD
Department of Medicine in the division of Oncology
Washington University School of Medicine
Title: “The Evil side of gene regulation in acute myeloid leukemia”
Hosted By: Aaron Viny MD
E.P. Evans MDS Center Special Seminar:
Wednesday, January 17 ,2024
12:00 PM to 1:00 PM
ICRC first floor auditorium
Christin Zhang, PhD
Department of Hematology
Erasmus University Cancer Center, The Netherlands.
Title: TBD
Hosted By: Stavroula Kousteni PhD
MDS Faculty Meeting & Seminar:
Tuesday, January 9 ,2024
12:00PM to 1:30PM
Black Building, Conference Room 1418
Speaker: Dr. Raul Rabadan
Title: “Language models of regulation for cancer genetics”
E.P. Evans MDS Center Trainee Workshop Series Presentations
Wednesday, December 13, 2023
12:00 PM to 2:00PM
Black Building room 1418
Pizza & refreshments provided
Presenter: Lee, Katherine from Zha lab
Ahn, Yong-Oon from Mace lab
MDS Member Anoucements
Congratulations on all the trainees who will present at American Society of Hematology annual meeting in San Diego!
Dr. Emily Mace was rewarded with new R01 grant
Emily was recently rewarded a new R01 grant (R01GM148504) from the National Institute of Health entitled “Defining the functional role of CD56 on human natural killer cells. The aims of this project are to dissect the molecular mechanisms of NCAM/CD56 function on human NK cell function.
New Publications from Center Members:
Riabov V, Xu Q, Schmitt N, Streuer A, Ge G, Bolanos L, Wunderlich M, Jann JC, Wein A, Altrock E, Demmerle M, Mukherjee S, Ali AM, Rapp F, Nowak V, Weimer N, Obländer J, Palme I, Göl M, Jawhar A, Darwich A, Wuchter P, Weiss C, Raza A, Foulks JM, Starczynowski DT, Yang FC, Metzgeroth G, Steiner L, Jawhar M, Hofmann WK, Nowak D.
ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms.
Haematologica. 2023 Nov 2. doi: 10.3324/haematol.2023.282921. Epub ahead of print. PMID: 37916386.
Burke A, Borot F, Du X, Churchill M, Ding J, Grass AM, DeSouza P, Ali AM, Mukherjee S.
A novel therapeutic bispecific format based on synthetic orthogonal heterodimers enables T cell activity against Acute myeloid leukemia.
Oncogene. 2023 Jan;42(1):26-34. doi: 10.1038/s41388-022-02532-2. Epub 2022 Nov 10. PMID: 36357573.
Qin Y, Mace EM, Barton JP.
An inference model gives insights into innate immune adaptation and repertoire diversity.
Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2305859120. doi: 10.1073/pnas.2305859120. Epub 2023 Sep 11. PMID: 37695895; PMCID: PMC10515141.
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Other Events
HICCC Programs
Thursday, December 14, 2023
4:00 PM - 5:00 PM
Monthly Columbia Trainee Community Cancer Research Conference
Tuesday, December 12, 2023
11:00 PM
Call for Applications Deadline: Joint Precision Medicine Pilot Award
Friday, December 15, 2023
12:00 PM - 2:00 PM
Cancer-Related Specific Aims Mock Study Section
The Herbert Irving Comprehensive Cancer Center (HICCC) is launching a new workshop, "Cancer-Related Specific Aims Mock Study Section," an exclusive opportunity for assistant professors pursuing cancer-related grants. This workshop is designed to build off the “Writing Specific Aims” workshop offered by the VP&S Office of Research on November 17 from 12:00 to 1:30 pm.
HICCC Seminar Series: Research-in-Progress
Wednesday, December 20, 2023
4:00 PM - 5:00 PM
Ke Cheng, PhD
Professor of Biomedical Engineering
Department of Biomedical Engineering
Program: Tumor Biology and Microenvironment Program
Title: “Exosomes as "scouts" and "raiders" against cancer”
Other Seminars
IICD Special Seminar:
Tuesday, December 12, 2023
11:00 AM - 12:00 PM
Yuqi Tan, PhD
Stanford University
Title:” A spatial Biologist’s guide to decode multiplexed image analysis”
Seminars in Precision Medicine
Thursday, December 14, 2023
4:00 PM - 5:00 PM
Zhonghua Liu, PhD
Assistant Professor of Biostatistics in the Department of Biostatistics
Mailman School of Public Health, Columbia University
Title: “Robust Mendelian randomization coupled with Alphafold2 for drug target discovery”
CSCI Work-in-Progress Talk Series
Thursday, December 14, 2023
11:30 AM - 12:30 PM
Monica Kasbekar (Passegué Lab)
Title: "Age-associated chronic inflammation in normal and pre-leukemic human hematopoiesis"
Everardo Hegewisch Solloa (Mace Lab)
Title: “Defining the role of NCAM on stroma in human NK cell development"
G&D Seminar Series
Tuesday, December 5, 2023
4:00 PM - 5:00 PM
Sergej Djuranovic, PhD
Professor of Cell Biology & Physiology
Washington University School of Medicine in St. Louis
Title: “PolyA track associated frameshifting in stress and cancer”
Monday, December 11, 2023
4:30 PM - 5:30 PM
Diane Haakonsen, PhD
Helen Hay Whitney Postdoctoral Fellow
Department of Molecular and Cell Biology
University of California, Berkeley
Title "Mechanism and function of accurate stress response silencing"
Tuesday, December 12, 2023
4:00 PM - 5:00 PM
Katrin Karbstein, PhD
Professor
The Herbert Wertheim UF Scripps Institute for
Biomedical Innovation & Technology
Title: “Ribosome Repair and Remodeling Preserves the Integrity of the Ribosome Pool During Stress”
Wednesday, December 13, 2023
4:00 PM - 5:00 PM
Chelsea Lowther, PhD
Postdoctoral Research Fellow
Center for Genomic Medicine, Massachusetts General Hospital
Harvard Medical School
Title: "Interpreting the impact of structural variation on risk for neurodevelopmental and neuropsychiatric disorders"
Tuesday, December 19, 2023
4:00 PM - 5:00 PM
Luke Berchowitz, PhD
Assistant Professor of Genetics and Development (in the Taub Institute for Research on Alzheimer's Disease and-the Aging Brain)
Columbia University Medical Center
Title: TBA
The Biology of Aging Seminar Series
Wednesday, December 6, 2023
12:00 AM - 1:00 PM
Vadim Gladyshev, Ph.D
Professor, Medicine, Harvard Medical School
Director of Redox Medicine, Medicine
Brigham And Women's Hospital
Title: "Systems Insights into Aging, Lifespan Control and Rejuvenation "
Annual Dr. J. Thomas Bigger Lecture Series
Wednesday, December 6, 2023
12:00 PM - 1:00 PM
Kenneth D. Mandl, MD, MPH
Donald A.B. Lindberg Professor of Pediatrics & Professor of Biomedical Informatics
Harvard Medical School
Title: "Interconnected Intelligence: AI's Role in Reshaping 21st Century Digital Infrastructure"