Upcoming Programs and Events

Columbia Stem Cell Initiative (CSCI) Work in Progress (WIP) Series Thursday, February 9 11:30 AM Hammer Room 401   PRESENTERS: Sumin Jang/ Wichterle Lab “Human-specific motor neuron progenitors increase neurogenic timescales and motor neuron production”  Ning Wang/Dieter Egli Lab “DNA Replication Timing Alterations As A Potential Cause of Developmental Abnormalities In Prader-Willi Syndrome   An opportunity for Columbia’s community at large to learn about ongoing stem cell works happening in the labs affiliated with CSCI, and for CSCI trainee to receive feedback from the community. Each event will include two presentations by trainees of 20-minutes each, with time afterward for Q&A. Pizza and refreshments will be provided. For more info: ll3129@cumc.columbia.edu https://www.stemcell.columbia.edu/

On Friday, February 10, 2023, we are excited to welcome Prof. Rusty Lansford from USC as he presents, "Intravital Imaging Across Kingdoms." ABOUT THE SEMINAR Intravital Imaging Across Kingdoms Since 2011, I have worked at the University of Southern California (USC) & Children’s Hospital Los Angeles (CHLA) using a combination of experimental, computational, and theoretical approaches to quantitatively understand decision-making in single cells and tissues, focusing on questions in vascular, neural, and germ cell development. We have a quiver of new molecular tools that permit molecular perturbation to be induced in vivo with extreme spatiotemporal accuracy and generated new multispectral fluorescent sensors to assay changes in cell behaviors resulting from the molecular disruptions. The quail model system uncouples early embryogenesis from maternal influences, providing a simpler system to assay the complex and multifactorial effects of how germ cells act in their native environment during the equivalent of their first-trimester development. Recently we have been developing new spectral technologies to investigate marine-based cross-kingdom mutualistic interactions to advance understanding how diverse organisms adapt to their changing environment. ABOUT THE SPEAKER Russell D. “Rusty” Lansford, Ph.D., Associate Professor, University of Southern California Keck School of Medicine & Investigator at Children’s Hospital Los Angeles Rusty Lansford earned an A.B. in Immunology at UC Berkeley and worked with Dr. Marian Koshland on the regulation of the J chain protein transcriptional regulation. He obtained a Ph.D. in Molecular Immunology at Columbia University working with Dr. Fred Alt. Lansford worked as a postdoctoral researcher in Developmental Biology and Optics at Caltech with Dr. Scott Fraser working on neural crest cells migration and patterning and he co-developed multispectral imaging hardware and software now widely used in microscopy. As an independent investigator at Caltech, he developed transgenic quail as a model system to dynamically investigate embryogenesis.   ABOUT THE 2022-2023 BME SEMINAR SERIES The Department of Biomedical Engineering at Columbia University is proud to host an annual weekly seminar series on the latest developments and research in Biomedical Engineering. The weekly series takes place on Friday mornings at 11:00AM Eastern and includes a variety of renowned academics from top universities to talk about their specific research and experience. The January 21 seminar is a virtual event.

Heidi L. Rehm, PhD, FACMG Director, Genomic Medicine Unit, Center for Genomic Medicine, and Chief Genomics Officer, Department of Medicine, Massachusetts General Hospital Co-Director, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard Medical and Clinical Lab Director, Broad Clinical Laboratory Professor of Pathology, Harvard Medical School Our understanding of the genetic basis of disease has been rapidly advancing thanks to major technological advances in genomic sequencing and data analysis. Yet the majority of individuals with a suspected genetic disorder do not receive a molecular diagnosis. So where is the gap and how will we fill it? This talk will touch on major global efforts to collaborate in rare disease gene discovery, genomic and health data sharing, and expert curation of genomic knowledge. It will also touch on the translation and implementation of this work into routine medical practice and chart a path for the future. Thursday, February 16, 2023 - 4:00 to 5:00pm EST Zoom and In-person (622 West 168th St. PH-10-405A/B) Register to receive Zoom link Presented by the Precision Medicine Resource of the Irving Institute for Clinical and Translational Research.  This event is supported in part by a gift from Pfizer to Columbia.

Join us on Thursday, February 23rd, for our 7th Annual Engineering in Medicine Symposium, hosted by The Fu Foundation School of Engineering and Applied Science at Columbia University & Columbia University Irving Medical Center! Experience a day of talks by global leaders at the interface of engineering and medicine. Register now!   VIEW THE PROGRAM AND SPEAKER BIOS HERE