In this series, directors of shared resource/core facilities will describe the science of the technologies of their respective facilities, how they are used, their application to cutting-edge research and discovery, the latest innovations, and the future directions of the field. In this seminar, Jianwen Que, PhD, Director of the HICCC Genetically Modified Mouse Models Shared Resource and Barbara Corneo, PhD, Director of the Columbia Stem Cell Core Facility, will describe their facilities.

In this series, directors of shared resource/core facilities will describe the science of the technologies of their respective facilities, how they are used, their application to cutting-edge research and discovery, the latest innovations, and the future directions of the field. In this seminar, Remi Creusot, PhD, Director of the HICCC Flow Cytometry Shared Resource and Hanina Hibshoosh, MD, Director of the HICCC Molecular Pathology Shared Resource, will describe their facilities.

5:00 PM: Welcome Jason D. Wright, MD, Sol Goldman Associate Professor of Gynecologic Oncology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:05 PM: Surgical Innovations for Uterine Cancer Fady Khoury-Collado, MD, Assistant Professor of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:25 PM: Emerging Paradigms in Radiation and Adjuvant Therapy Cristine Chin, MD, Assistant Professor of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:45 PM: Immunotherapy and Novel Therapeutics for Recurrent Disease June Hou, MD, Assistant Professor of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 6:05 PM: Q&A 6:30 PM: Adjourn This activity has been approved for AMA PRA Category 1 Credit™

The program will examine hereditary ovarian cancer including how genetic testing is being utilized to identify high-risk women and to tailor therapy for women with ovarian cancer, new surgical and chemotherapeutic options for the initial management of ovarian cancer, and novel therapeutic approaches for women with recurrent ovarian cancer. The target audience includes oncologists, obstetricians/gynecologists, and primary care providers. At the conclusion of this activity, participants should be able to: • Discuss the advances and potential limitations of genomic medicine in providing early detection, risk assessment, treatment guidance to women at high risk for developing hereditary breast and ovarian cancer. • Discuss the treatment of recurrent epithelial ovarian cancer for platinum sensitive and platinum resistant patients, including new targeted therapies. AGENDA 5:00 PM: Welcome Jason D. Wright, MD, Sol Goldman Associate Professor of Gynecologic Oncology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:05 PM: Hereditary Ovarian Cancer June Hou, MD, Assistant Professor of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:25 PM: Upfront Surgery and Chemotherapy Options Caryn St. Clair, MD, Assistant Professor of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 5:45 PM: New Treatments for Recurrent Ovarian Cancer Allison Gockley, MD, Assistant Professor of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York 6:05 PM Q&A 6:30 PM Adjourn This activity has been approved for AMA PRA Category 1 Credit™