A Phase 1/1b Open-Label Dose Escalation and Expansion Study of Bcl-2 Inhibitor BGB-11417 inPatients with Mature B-Cell Malignancies

Contact:

NCT Number:

Protocol:

AAAT5414

Study Status:

Active/Enrolling

Population:

Adult

Phase:

I

The purpose of this study is to look at the safety and tolerability of an investigational anticancer drug currently known as BGB-11417. This study aims to determine the range of BGB-11417 doses that can safely be used, the safest dosing schedule to minimize side effects when first taking BGB-11417, what side effects may be experienced when taking this drug, how your body processes this drug, and if this drug is effective against your cancer.

Are you Eligible? (Inclusion Criteria)

  • Provision of signed and dated written informed consent prior to any study specific procedures, sampling, or analyses
  • Age 18 years or older
  • Confirmed diagnosis of one of the following

Specialty Area(s)

Leukemia

Principal Investigator

Trial Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032