Charles J. Lightdale, MD

Cancer Care
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Current research is focussed on Barrett's esophagus. Targeted biopsies using confocal endomicroscopy for more accurate diagnosis. Radiofrequency ablation of Barrett's esophagus. Endoscopic mucosal resection of pre-cancerous lesions and early cancer. Blood tests and biopsy tests for early detection of esophageal cancer. Prevention of esophageal cancer in Barrett's esophagus.

Areas of Expertise / Conditions Treated

  • Barrett's Esophagus
  • Cancer Prevention
  • Capsule Endoscopy
  • Esophageal Disease
  • Esophagus Disorder
  • Gastrointestinal (GI) Endoscopy Procedures
  • Gastrointestinal Cancer
  • Gastrointestinal Disorder
  • Pancreatic Cancer
  • Second Opinion
  • Swallowing Disorder

Academic Appointments

  • Professor of Medicine at CUMC

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Male

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180 Fort Washington Avenue
New York, NY 10032

Credentials & Experience

Education & Training

  • Columbia University College of Physicians and Surgeons
  • Internship: Yale-New Haven Hospital
  • Residency: New York Hospital - Cornell Medical Center
  • Residency: Yale-New Haven Hospital
  • Fellowship: New York Hospital - Cornell Medical Center

Board Certifications

  • Gastroenterology
  • Internal Medicine
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I am a trained gastroenterologist with clinical expertise in the areas of pancreatic cancer, Barrett’s esophagus, and other related diseases. My specialties include digestive and liver disorders, gastroenterology, and cancer. I have authored over 130 scientific articles in peer-reviewed journals, 290 reviews, editorials, and book chapters. I have served on two consecutive 4-year terms as Editorin-Chief of Gastrointestinal Endoscopy, the official journal of the ASGE. Identifying ways to prevent upper-GI cancers is the main goal of my research. My research areas include studying Barrett's esophagus; targeted biopsies using confocal endomicroscopy for more accurate diagnosis; radiofrequency ablation of Barrett's esophagus; endoscopic mucosal resection of pre-cancerous lesions and early cancer. I have also worked extensively on developing blood and biopsy tests for early detection and prevention of esophageal cancers; and the use of endoscopic ultrasound for diagnosis and staging of gastrointestinal cancers.

Selected Publications

  • Lightdale CJ. Gastroesophageal Reflux Disease: Changing the Conversation. Gastrointest Endosc Clin N Am. 2020 Apr;30(2):xi-xii. doi: 10.1016/j.giec.2020.02.001. PMID: 32146952
  • Ginès A, Lightdale CJ. How I do a diagnostic EUS. Endoscopy. 2019; 51(10):973-975. PMID: 31307101
  • Goldblum JR, Shaheen NJ, Vennalaganti PR, Sharma P, Lightdale CJ. WATS for Barrett's surveillance. Gastrointest Endosc. 2018 Jul;88(1):201-202. PMID: 29935618