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Showing 291 - 300 of 301 Trials

  • Efficacy of a Pill-Dispensing System to Increase Disposal of Unused Opioids and to Reduce Refills after Cancer-Related Surgery

    Principal Investigator:

    Dawn L Hershman, MD

    Contact Number:

    212-342-5162

    Population:

    Adult

    Phase:

    NA
    - Are you of 18 years or older? - Do you have upcoming open, non-laparoscopic surgery? - Is it planned that you will receive opioids in the post-operative period? - Are you able to download and use a iPhone or iPad application? Are you Eligible? (Inclusion Criteria) Are you of 18 years or older? Do you have upcoming open, non-laparoscopic surgery? Is it planned that you will receive opioids in the post-operative period? Are you able to download and use a iPhone or iPad application?

  • Implementing a Low Glycemic Diet in Children and Adolescents Undergoing Treatment for Acute Lymphoblastic Leukemia

    Principal Investigator:

    Elena J. Ladas, PhD, RD

    Contact Number:

    (212) 342-5162

    NCT Number:

    NCT03157323

    Population:

    Pediatrics/Adult

    Phase:

    NA
    The purpose of this study is to determine the feasibility, measured by compliance to a low-GI diet, of a 6-month low glycemic dietary intervention in children and adolescents undergoing treatment for ALL. Are you Eligible? (Inclusion Criteria) (1) Children and adolescents diagnosed with ALL between the age of 5-21 years of age, (2) Within three days of starting the induction phase of therapy for ALL (B- Cell, T-Cell, or Mixed Phenotype), and (3) Proficient in English or Spanish.

  • Improving Surgical Care and Outcomes in Older Cancer Patients Through Implementation of an Efficient Pre-Surgical Toolkit (OPTI-Surg)

    Principal Investigator:

    Bret Taback, MD

    Contact Number:

    (212) 342-5162

    NCT Number:

    NCT03857620

    Population:

    Adult

    Phase:

    NA
    Surgery is the main treatment for many cancer conditions. In many elderly patients, surgery can greatly affect physical condition, and the ability to return to pre-surgery levels of physical functioning. By providing some simple pre-surgical recommendations, it may be possible to improve the rate of recovery from surgery and the possibility that patients will return to their pre-surgery levels of function. Your doctors are participating in a study to determine if a change in how they evaluate and manage elderly patients will improve recovery rates from major cancer surgery. Doctors and...

  • Improving Patient-Centered Communication in Breast Cancer: A RCT of a Shared Decision Engagement System (SHARES)

    Principal Investigator:

    Bret Taback, MD

    Contact Number:

    212-342-5162

    NCT Number:

    NCT04549571

    Population:

    Adult

    Phase:

    NA
    This study is being done to answer the following question: How can we best help patients and their clinicians make decisions about breast cancer treatment (surgery and other treatments, like radiation and chemotherapy)? We are doing this study because we want to better understand how to support patients in making decisions about breast cancer treatment. We want to see if new approaches to support patient decision-making and patient-clinician communication about breast cancer treatment are better than existing or usual approaches. We are testing two interventions, one for patients and one for...

  • IMPACT Trial: Intervention to iMProve AdherenCe equitably

    Principal Investigator:

    Dawn L Hershman, MD

    Contact Number:

    212-342-5162

    Population:

    Adult

    Phase:

    NA
    Many patients with breast cancer, who also take medicine to prevent heart disease such as a blood pressure medicine or a cholesterol medicine, experience frustration with the large number and difficult scheduling of their medications, known as “pill burden”. This study will help us find out how much “pill burden” exists in subjects with cancer at various stages, and how this intervention can help. Results of this study may help us figure out the best way to help patients manage their medications in the future. Are you Eligible? (Inclusion Criteria) Are you diagnosed...

  • Nitrous Oxide For Endoscopic Ablation of Refractory Barrett’s Esophagus (NO FEAR-BE)

    Principal Investigator:

    Julian Adin Abrams, MD

    Contact Number:

    212-342-5162

    NCT Number:

    NCT03554356

    Population:

    Adult

    Phase:

    NA
    dy is to evaluate the safety and effectiveness of using the C2 CryoBalloon Focal Ablation System to treat any remaining Barrett’s Esophagus after receiving Radiofrequency Ablation (RFA). Are you Eligible? (Inclusion Criteria) Are you at least 18 years of age? Do you have a history of esophageal cancer? Are you willing to undergo an experimental treatment for your type of cancer?

  • Precision Oncology in Advanced Pancreatic Cancer.

    Principal Investigator:

    Gulam A. Manji, MD

    Contact Number:

    212-342-5162

    NCT Number:

    NCT04476537

    Population:

    Adult

    Phase:

    NA
    The purpose of this study is to match individual tumors with the drug or drug combinations that are most likely to destroy those tumors. The purpose of using Ruxolitinib, Imatinib, or Capecitabine to treat your pancreas cancer is to determine whether it is safe and effective in stopping pancreas cancer growth in patients who have already received one or two lines of chemotherapy. Are you Eligible? (Inclusion Criteria) Are you older than 18 years old? Do you have histologically or cytologically confirmed diagnosis of pancreatic ductal adenocarcinoma? Do you have a life expectancy of greater...

  • RANDOMIZED NON-INFERIORITY TRIAL COMPARING OVERALL SURVIVAL OF PATIENTS MONITORED WITH SERUM TUMOR MARKER DIRECTED DISEASE MONITORING (STMDDM) VERSUS USUAL CARE IN PATIENTS WITH METASTATIC HORMONE RECEPTOR POSITIVE BREAST CANCER

    Principal Investigator:

    Melissa Accordino, MD

    Contact Number:

    (212) 342-5162

    NCT Number:

    NCT03723928

    Population:

    Adult

    Phase:

    NA
    The purpose of this study is to determine if overall survival of patients monitored with serum tumor marker direct disease monitoring (STMDDM) is as good as the overall survival of patients monitored with the usual care. Are you Eligible? (Inclusion Criteria) Do you have hormone positive, HER-2 negative, metastatic breast cancer? Are you 18 years of age or older? Are you willing to be monitored for your disease for the duration of this study?

  • The Acceptability of a Rapid Esophageal Adenocarcinoma Risk Test (REACT)

    Principal Investigator:

    Julian Adin Abrams, MD

    Contact Number:

    (212) 342-5162

    NCT Number:

    NCT03366012

    Population:

    Adult

    Phase:

    NA
    This study aims to evaluate the acceptability of a new non-invasive screening device to test for Barrett's esophagus. The investigators will prospectively enroll 100 patients to undergo Cytosponge testing. The time of involvement for an individual will range from 2 weeks to 2 months, depending on the results of the Cytosponge test and time to follow up endoscopy, if indicated. The Cytosponge consists of a 3cm diameter, polyester, medical grade spherical sponge on a string, compressed within a gelatin capsule. The capsule is swallowed while the patient or the research specialist holds onto the...

  • Trial of a Smartphone Application to Improve Medication Adherence among Patients with Cancer

    Principal Investigator:

    Melissa Accordino, MD

    Contact Number:

    (212) 342-5162

    Population:

    Adult

    Phase:

    NA
    The purpose of this study is to learn about the difficulties patients have with the amount of medication they are required to take and to see if a smart phone application can make that process easier for patients. Patients will be asked to use an application on their smartphone or tablet daily and to come to the clinic once a month for 3 months. Are you Eligible? (Inclusion Criteria) Do you have advanced or metastatic cancer, or a hematologic malignancy? Are you taking, or planning to take at least one oral anti-cancer drug? Do you have access to a mobile phone or tablet that can download...

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