MajesTEC-9: A Phase 3 Randomized Study Comparing Teclistamab Monotherapy versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants with Relapsed or Refractory Multiple Myeloma who have Received 1 to 3 Prior


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The purpose of this study is to see how teclistamab by itself compares to study treatment combinations that are commonly used to treat multiple myeloma. These study treatment combinations are either pomalidomide, bortezomib and dexamethasone, called PVd, or carfilzomib and dexamethasone, called Kd. The patients will be randomly assigned to on of the study groups. The term randomized means something is done by chance or without any particular pattern, like flipping a coin to decide an outcome.

Are you Eligible? (Inclusion Criteria)

  • Are you at least 18 years of age or older? - Do you have a documented diagnosis of multiple myeloma? - Do you have an Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0 to 2? ECOG PS describes a patient's level of functioning in terms of ability to care for oneself, daily activities and physical ability.

Specialty Area(s)

Multiple Myeloma/Amyloidosis

Principal Investigator

Trial Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032