Michael S. Hughes, MD
On the web
Overview
Dr. Michael Hughes is an attending physician and Assistant Professor practicing at Columbia University Irving Medical Center. He received his A.B. in Classics magna cum laude from Harvard College and his MD cum laude from Harvard Medical School. He completed his Internal Medicine residency at the Johns Hopkins Bayview Medical Center and Hematology/Oncology fellowship at the Columbia University Irving Medical Center. He is a member of the American College of Physicians, the American Medical Association, the American Society of Hematology, and the American Society of Clinical Oncology.
Dr. Hughes' research has explored the interplay between cancer and the immune system. As an undergraduate medical student, he studied immune checkpoint inhibitor-induced gastroenterocolitis. As a Johns Hopkins Physician Scientist Training Pathway Scholar during residency, he investigated outcomes in patients with peripheral T-cell lymphomas after haploidentical blood and marrow transplantation. As an NIH T32-supported fellow, he worked in the Lentzsch Laboratory to develop novel anti-AL amyloidosis fibril therapies. For his contributions, Dr. Hughes was awarded the 2024 ASCO/Conquer Cancer Young Investigator Award and the 2025 Amyloidosis Foundation Research Grant.
Dr. Hughes cares primarily for patients with plasma cell disorders, including multiple myeloma, amyloidosis, MGUS, POEMS syndrome, and Waldenstrom's macroglobulinemia. His current translational research interests focus on machine learning/deep learning-assisted outcome prediction in these diseases and the ongoing development of novel anti-AL amyloidosis fibril strategies.
Academic Appointments
- Assistant Professor of Medicine at CUMC
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Location(s)
Insurance Accepted
Aetna
- Aetna Signature Administrators
- EPO
- HMO
- Medicare Managed Care
- NY Signature
- POS
- PPO
- Student Health
Affinity Health Plan
- Essential Plan
- Medicaid Managed Care
Amida Care
- Special Needs
Cigna
- EPO
- Great West (National)
- HMO
- Medicare Managed Care
- POS
- PPO
Emblem/GHI
- Medicare Managed Care
- PPO
Emblem/HIP
- ConnectiCare
- EPO
- Essential Plan
- HMO
- Medicaid Managed Care
- Medicare Managed Care
- POS
- PPO
- Select Care (Exchange)
- Vytra
Empire Blue Cross/Blue Shield
- EPO
- HMO
- Medicare Managed Care
- PPO
Empire Blue Cross Blue Shield HealthPlus
- Child/Family Health Plus
- Essential Plan
- Medicaid Managed Care
Fidelis Care
- Child/Family Health Plus
- Essential Plan
- Medicaid Managed Care
- Medicare Managed Care
Healthfirst
- Child/Family Health Plus
- Leaf (Exchange)
- Medicaid Managed Care
- Medicare Managed Care
Local 1199
- Local 1199
MagnaCare (National)
- MagnaCare
Medicare
- Traditional Medicare
Multiplan
- Multiplan
MVP Health Care
- Child/Family Health Plus
- Essential Plan
- HMO
- Medicaid Managed Care
RiverSpring
- Special Needs
UnitedHealthcare
- Compass (Exchange)
- Empire Plan
- HMO
- Medicaid (Community Plan)
- Medicare Managed Care
- Oxford Freedom
- Oxford HMO
- Oxford Liberty
- POS
- PPO
VNSNY CHOICE
- Medicare Managed Care
- SelectHealth
- Special Needs
WellCare
- Medicaid Managed Care
- Medicare Managed Care
World Trade Center Health Plan
- World Trade Center Health Plan
Credentials & Experience
Education & Training
- Harvard Medical School
- Internship: Internal Medicine, Johns Hopkins Bayview Medical Center
- Fellowship: Hematology/Oncology, Columbia University Irving Medical Center
Honors & Awards
- 2023: Columbia University Irving Medical Center T32 grant recipient
- 2022: Johns Hopkins Bayview Randy Barker Medical Group Award for Excellence
- 2021: Johns Hopkins University School of Medicine Distinguished Teaching Society Finalist
- 2015: Harvard University, William King Richardson Scholarship
- 2014: Harvard University, Harvard Presidential Public Service Fellowship, Edward M. Lamont Public Service Fellowship