Asher J Williams, PhD

  • Assistant Professor of Chemical Engineering, Columbia University
  • Affiliate Faculty, Zuckerman Mind Brain Behavior Institute
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Overview

Asher Williams, PhD is an Assistant Professor in the Department of Chemical Engineering at Columbia University and an affiliate of the Zuckerman Mind Brain Behavior Institute. She is a member of the Tumor Biology and Microenvironment program at the Herbert Irving Comprehensive Cancer Center (HICCC). Dr. Williams develops molecular engineering strategies to understand and manipulate protein–glycan interactions for therapeutic and diagnostic applications. Her research integrates protein engineering, glycobiology, and synthetic biology to develop new approaches for targeting disease-associated glycans in cancer, infectious disease, and neurodegenerative disorders. Her laboratory designs engineered lectins, glycan-binding proteins, and glycan-targeted nanobody conjugates to probe and modulate glycan-mediated biological processes. The lab also develops cell-free biosynthetic platforms for producing glycoconjugate vaccines and other glycan-based therapeutics. She received her PhD in Chemical Engineering from Rensselaer Polytechnic Institute and completed her postdoctoral training in Chemical Engineering at Cornell University.

Academic Appointments

  • Assistant Professor of Chemical Engineering, Columbia University
  • Affiliate Faculty, Zuckerman Mind Brain Behavior Institute

Credentials & Experience

Education & Training

  • PhD, Chemical Engineering, Rensselaer Polytechnic Institute
  • BS, Chemical & Biomolecular Engineering, New York University Polytechnic School of Engineering

Committees, Societies, Councils

  • American Institute of Chemical Engineers
  • National Society of Black Engineers
  • American Chemical Society
  • Tau Beta Pi Engineering Honor Society
  • Omega Chi Epsilon National Honor Society for Chemical Engineering
  • National Organization for the Professional Advancement of Black Chemists and Chemical Engineers
  • National Black Postdoctoral Association

Honors & Awards

  • ACS Talented 12 Nominee (2026)
  • Faculty Access Program Cohort IV (2025)
  • Inaugural 2030STEM × Burroughs Wellcome Fund Fellow (2025)
  • Janette and Armen Avanessians Diversity Award, Columbia University (2025)
  • G7 Summit Vaccine Luminary, UK Cabinet Office (2021)
  • Cell Press “1000 Inspiring Black Scientists in America” (2020)
  • MIT Rising Star in Chemical Engineering (2020)

Research

Asher Williams’ research lies at the intersection of synthetic glycobiology, protein engineering, and immunoengineering.
The Williams Lab at Columbia University develops molecular tools to study and engineer glycan-mediated biological processes. Our research integrates protein engineering, synthetic biology, and glycobiology to design next-generation therapeutic and diagnostic platforms. We focus on engineering glycan-binding proteins and lectins with programmable specificity to target disease-associated glycans and modulate immune responses. Our work spans the development of glycan-targeted therapeutics, engineered vaccine platforms, and new technologies for interrogating glycan-mediated signaling in disease.

Key Research Areas
Engineering lectins and glycan-binding proteins with programmable specificity
Glycan–nanobody conjugates for targeted immune modulation
Cell-free biosynthesis of glycoconjugate vaccines and glycan-based therapeutics
Molecular tools for probing glycan-mediated signaling in cancer and infectious diseases
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