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40 years of breast cancer awareness has helped save many lives through screening and treatment advances. Dr. Katherine Crew notes progress in targeted therapies, but warns that disparities remain.

Columbia researchers found that combining CDK4/6 and CDK7 inhibitors blocks tumor growth and resistance in hormone receptor–positive and triple-negative breast cancers while boosting immune response.

Known risk factors, including genetics and lifestyle, do not fully explain the upward trend of breast cancer rates.

The award recognizes Sadelain’s pioneering role in the development of CAR-T cells for cancer therapy.