A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging


NCT Number:



Study Status:






The purpose of the study is to evaluate the tolerability of a ketogenic diet in conjunction with metformin in people with malignant glioma. The study doctors will try to determine if maintaining the ketogenic diet with metformin will have any effect on your tumor.

Are you Eligible? (Inclusion Criteria)

  • Have you been diagnosed with high-grade glioma?
  • Are you 18 years of age or older?
  • Do you not have Type 1 or Type 2 diabetes?
  • Have you not received prior treatment with Bevacizumab and are you not receiving any other investigational agents?

Specialty Area(s)

Principal Investigator

Profile Headshot
  • Chief, Division of Neuro-Oncology
  • Co-Director, Brain Tumor Center
  • Associate Director for Clinical Trials, Herbert Irving Comprehensive Cancer Center
  • Associate Dean of Clinical Trials at VP&S

Trial Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032