A multi-site, open-label, Phase II, randomized, controlled trial to compare the efficacy of RO7198457 versus watchful waiting in resected, Stage II(high risk) and Stage III colorectal cancer patients who are ctDNA positivefollowing resection

Contact:

NCT Number:

Protocol:

AAAT4655

Study Status:

Active/Enrolling

Population:

Adult

Phase:

II

The BNT122-01 research study is testing an investigational medication (RO7198457) for patients who have had surgery for Stage II and Stage III colorectal cancer. The study will look at the safety and effectiveness of an investigational medication for patients who have had surgery for Stage II (high risk) and Stage III colorectal cancer. It will study whether it will lead to a longer period of time before recurrence or spread of cancer compared with watchful waiting.

Are you Eligible? (Inclusion Criteria)

  • • Do you have Stage II/III rectal cancer or Stage II (high risk)/III colon cancer
  • that has been surgically removed followed by chemotherapy?
  • • Did you have detectable levels of DNA from tumor cells in blood work prior to
  • start of chemotherapy?
  • • Have you not received chemotherapy before surgery?

Specialty Area(s)

Principal Investigator

Trial Location(s)

CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032